Endocrine Abstracts

There have been few epidemiologic studies on vitamin D status in postmenopausal women of Middle East countries.The purpose of this study was to investigate the 25-hydroxyvitamin D levels in postmenopausal women of Iran. By using the records of the local household registry, a sample of 300 subjects was drawn by simple random sampling. Serum 25-hydroxyvitamin D levels were determined with full automated chemiluminescent immunoassay. In addition, the study ...

Background: Oxidized low-density lipoprotein (Ox-LDL) is a key factor in the development of arteriosclerosis. It can cause endothelial dysfunction and augment lipid accumulation within the arterial wall. Increased oxidative stress in diabetes contributes to this process. Ox-LDL is a highly immunogenic molecule and it is not clear whether oxidized LDL antibodies (OLAB) are pathogenic or protective in arteriosclerosis? The aim of this study was to evaluate Ox-LDL and its antibod...

Introduction: Metformin is the only biguanide that is currently in use as an oral hypoglycemic agent in type 2 diabetes mellitus (DM). There are reports about the vitamin B12 deficiency in metformin users. This study was aimed to evaluate the vitamin B12 deficiency in patients with type 2 DM using metformin or other hypoglycemic agents.Methods: A descriptive-comparative study was performed on 400 patients with type 2 DM presenting t...

Objectives: The present study aimed to investigate the prevalence of thyroid dysfunction in the elderly women of Tabriz city, the largest city in North West Iran.Design: Cross-sectional study.Setting and participants: By using the records of the local household registry, a sample of 1150 subjects was drawn by simple random sampling. After the exclusion of nonresponse subjects, 1000 subjects aged between 60 and 89 years (mean 64.5&#...

The endothelial dysfunction and atherosclerosis. Recent studies have demonstrated that the amount of oxidized LDL (Ox-LDL) in plasma is correlated with IR in non-diabetic population. The intent of this study was to evaluate correlation of Ox-LDL and IR in diabetic patients, and to compare it with normal individuals.Methods: A total of 150 individuals aged 40 to 65 years were studied including 81 type 2 diabetic patients and 69 non-diabetic sex and BMI ma...

Introduction: Urtica diocia extract has been used for treatment of diabetes mellitus for many centuries. Hypoglycemic effects of U. diocia have been shown in multiple studies. The present study was designed to determinutese the possible mechanisms of hypoglycemic effects of U. diocia on RIN5F Rat Pancreatic β cells.Methods and materials: In cell culture laboratory of Drug Applied Research Center of Tabriz University (Medical Sci...